Figure 2 | Scientific Reports

Figure 2

From: MHCII expression on gut macrophages supports T cell homeostasis and is regulated by microbiota and ontogeny

Figure 2

Differential kinetics of MHCII expression on macrophages in the small intestine and colon during neonatal development. (a) Representative FACS plots of MHCII and Tim4 expression on SI and LI macrophages of wild-type SPF mice at the indicated times after birth. (b-d) The graphs show the percentage of MHCIIhi cells within the total macrophages (b), or among Tim4- (c) or Tim4+ (d) populations in the SI (red) and LI (blue) at indicated time-points after birth. Each point represents the mean ± SD of four mice from two independent experiments. Statistical comparisons were performed using two-way ANOVA with Bonferroni’s multiple comparison test with a Sidak correction. Asterisks denote statistical significance between adjacent time points (*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001).

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