Figure 3
From: RNA disruption is a widespread phenomenon associated with stress-induced cell death in tumour cells
RNA disruption induced by various cellular stressors in multiple cell lines. A2780 (a), K562 (b), MDA-MB-231 (c) and A375 (d) cells were exposed to various cellular stressors for 72 h. Total RNA was isolated from cells following drug treatment, and RNA disruption was analyzed using the RDA. Data are presented as means ± standard deviation, with individual data points shown in red. Groups labelled with an asterisk possess a normalized RDI that is significantly greater than that of the untreated control (blue dotted line). See Supplementary Table S2 for detailed results of each statistical test. TPG thapsigargin, TUN tunicamycin, CHX cycloheximide, Medium, standard culture medium diluted to 5 or 10% in PBS.
