Table 1 Patient characteristics.

From: Association between pazopanib exposure and safety in Japanese patients with renal cell carcinoma or soft tissue sarcoma

 

RCC

STS

n = 14

n = 19

Age (years), median

range

67.5

52–74

39

21–75

BSA(m2), median

range

1.77

1.53–2.32

1.67

1.30–2.20

Sex, Male/Female

13/1

8/11

Ccr (mL/min), median

range

79.0

39–189

119

44.2–190

AST (IU/L), median

range

19.5

14–43

22

12–60

ALT (IU/L), median

range

18.5

9–34

22

7–130

T.Bil (mg/dL), median

range

0.6

0.2–0.9

0.40

0.2–1.7

ALB (g/dL), median

range

4.2

3.1–4.5

4.2

2.1–48

Administration of antacids

  

     No antacids

7

13

     PPI, yes

3

4

     H2-receptor blocker, yes

4

2

  1. BSA, Body surface area; CCr, Creatinine clearance; AST, Aspartate aminotransferase; ALT, Alanine aminotransferase; T.Bil, Total bilirubin; ALB, Albumin; PPI, Proton pump inhibitor; H2 blocker, Histamine 2 blocker.
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