Table 2 Hepatic function test values during treatment and pazopanib plasma trough concentrations.

From: Association between pazopanib exposure and safety in Japanese patients with renal cell carcinoma or soft tissue sarcoma

 

r

95% confidence interval

p-value

AST (IU/L)

0.492

0.1785–0.7144

0.004

ALT (IU/L)

0.434

0.1071–0.6768

0.012

T.Bil (mg/dL)

0.313

− 0.0339–0.5926

0.076

  1. Statistical tests were compared using univariate correlation analysis; r represents Pearson’s correlation coefficient.
  2. AST, Aspartate aminotransferase; ALT, Alanine aminotransferase; T.Bil, Total bilirubin.