Figure 3 | Scientific Reports

Figure 3

From: Self-association of the glycopeptide antibiotic teicoplanin A2 in aqueous solution studied by molecular hydrodynamics

Figure 3

Change of apparent sedimentation coefficient (s20,w) of teicoplanin A2 with sedimenting concentration, c. Concentrations were corrected for radial dilution. The extrapolated value of ~ 4.65 S is consistent with a spherical 18–19-mer of molar mass of 35,400 g/mol. The lower extrapolated value of ~ 0.7 S is the predicted value for a spheroidal unimer, which is consistent with the s-value of teicoplanin dissolved in 6 M GuHCl, s20,w = (1.17 ± 0.01) S. Solid line is a standard French curve fit to the data.

Back to article page