Table 2 Characteristics of the studies used to investigate the effect of anthocyanins on the short chain fatty acids [SCFA’s].
Animal | Age [weeks] | Model type | Source | Intervention compound | Dose | Duration [weeks] | References | Doi | |
|---|---|---|---|---|---|---|---|---|---|
1 | Male C57BL/6 J mice | 8 | High fat, high sucrose diet | Blueberry | Fruits dried | 727.2 mg/kg body weight | 8 | ||
Anthocyanins [Size based fractionation] | 77.3 mg/kg body weight | ||||||||
Proanthocyanins [Size based fractionation] | 4.6 mg/kg body weight | ||||||||
2 | Kunming mice | NA | Diphenoxylate induced constipation | Mulberry | Fruit dried | 142 mg/kg body weight [L] | 2 | ||
284.1 mg/kg body weight [M] | |||||||||
568.1 mg/kg body weight [H] | |||||||||
Anthocyanins | 0.7 [L], 1.4 [M], and 6.82 [H] mg/kg body weight | ||||||||
3 | Male C57BL/6 mice | 6 | Western diet | Montmorency tart cherry | Fruit dried | 5681.3 mg/kg of body weight [L] | 12 | ||
11,362 mg/kg of body weight [H] | |||||||||
Anthocyanins | 1.58 [L], 3.16 [H] mg/kg of body weight | ||||||||
4 | Male C57BL/6 mice | 4–5 | High fat diet | Raspberry | Fruit pulp hydro-acidified methanolic extract [Anthocyanins] | 22.8 mg/kg body weight | 12 | ||
5 | Male db/db mice with C57BL/6 J background | 6 | Diabetic Mice | Wild raspberry | Fruit hydro-acidified methanolic extract [Anthocyanins] | 150 mg/kg of body weight | 8 | ||
6 | Male C57BL6/J mice | 6 | High fat, cholesterol diet | Black rice | Fruit based commercial extract [Anthocyanins] | 13.6 mg/kg body weight [L] | 12 | ||
27.3 mg/kg body weight [M] | |||||||||
54.6 mg/kg body weight [H] | |||||||||
7 | Male Wistar rats | 3 | Normal | Brazilian berry | Fruit peel water extract [Phenolic extract] | Undefined | 7 | ||
8 | Male Wistar rats | 3 | Colitis model | Brazilian berry | Fruit peel water extract [Phenolic extract] | 141 and 151 mg/kg of body weight mg/kg of body weight [Short term treatment-L] | 7 | ||
215 and 208 mg/kg of body weight mg/kg of body weight [Long term treatment-H] | |||||||||
9 | Male Wistar rats | NA | High fat diet | Blueberry | Fruit Dried | 113.63 mg/kg body weight | 8 | ||
Phenolic + anthocyanin extract | 6.79 mg/kg body weight | ||||||||
10 | Male C57BL/6 mice | 5 | Normal | Russian box thorn | Fruit hydro-ethanolic extract [Phenolic extract] | 200 mg/kg of body weight | 12 | ||
11 | Male C57BL/6 J mice | 4 | High fat diet | Russian box thorn | Fruit Anthocyanins extract | 50 mg/kg body weight [L] | 12 | ||
100 mg/kg body weight [M] | |||||||||
200 mg/kg body weight [H] | |||||||||
12 | Male C57BL/6 mice | 5 | DSS-colitis model | Russian box thorn | Fruit hydro- ethanolic extract [Phenolic extract] | 200 mg/kg body weight [ACN:a, P3G:b] | 2.4 | ||
13 | Female C57BL/6 mice | 8 | Colon Cancer | Bilberry | Fruit based commercial powder [Anthocyanins] | 25 mg/kg body weight | 2 | ||
14 | Male C57BL/6 J mice | 6 | High fat, cholesterol diet | Sweet potato | Tuber based commercial powder [Anthocyanins] | 340.8 mg/kg body weight [L] | 12 | ||
681.8 mg/kg body weight [M] | |||||||||
1022.6 mg/kg body weight [H] |
