Table 6 All-inclusive, high-influencer subtracted and sub-group [intervention duration, dose, and animal model type] analysis to understand the effects of anthocyanins on the Butanoic acid.

From: Effect of anthocyanins on gut health markers, Firmicutes-Bacteroidetes ratio and short-chain fatty acids: a systematic review via meta-analysis

Study/ Subgroup type

SMD

95% CI

P value

I2[%]

Study duration

 < 4 weeks

0.93

− 0.80, 2.56

0.29

91

After removing Highly influencing studies

0.82

0.30, 1.34

0.002

0

 ≥ 4 weeks

1.81

0.90, 2.73

0.0001

90

After removing Highly influencing studies

1.30

0.36, 2.25

0.007

89

Dose of anthocyanin

Lower Dose

0.31

− 1.27, 1.89

0.70

90

After removing Highly influencing studies

0.97

− 0.57, 2.50

0.22

83

Higher Dose

3.08

1.50, 4.66

0.0001

86

After removing Highly influencing studies

3.32

1.53, 5.11

0.0003

79

Study model type

High fat diet model

3.64

2.31, 4.97

0.00001

92

After removing Highly influencing studies

3.34

1.65, 5.03

0.0001

93

Other models [Western diet, tumour, colitis]

0.33

− 0.57, 1.24

0.47

86

After removing Highly influencing studies

0.17

− 0.49,0.83

0.61

72

  1. Pooled effect sizes and 95% CI were determined using Random effects model.
  2. SMD Standardised mean difference, I2 Heterogeneity.