Table 3 Comparison of basic characteristics, semen parameters and malformation rate between three subgroups.

From: Correlation analysis of sperm DNA fragmentation index with semen parameters and the effect of sperm DFI on outcomes of ART

Parameter

IVF-I (n = 23)

IVF-II (n = 21)

IVF-III (n = 12)

χ2 or F

ICSI-I (n = 12)

ICSI-II (n = 15)

ICSI-III (n = 18)

χ2 or F

Female age (year)

32.00 ± 4.69

31.61 ± 4.72

32.85 ± 5.66

0.285

32.16 ± 4.97

31.75 ± 4.80

32.66 ± 4.02

0.503

BMI (kg/m2)

23.52 ± 3.01

22.06 ± 6.21

23.50 ± 3.36

0.551

23.01 ± 3.41

22.58 ± 3.52

24.02 ± 4.61

1.515

FSH (U/L)

5.89 (5.51,9.26)

6.83 (6.26,9.15)

5.90 (5.02,8.63)

2.205

7.82 (5.95,9.01)

8.3 (6.86,10.22)

6.86 (5.60,7.90)

4.052

Number of retrieved oocytes (piece)

12.00 (7.61,18.08)

12.00 (9.00,15.00)

12.00 (9.80,15.00)

0.519

11.0 (7.00,18.00)

11.0 (4.80,18.90)

12.00 (9.00,17.00)

0.819

Male age (year)

32.30 (29.00,39.00)

33.00 (30,38.00)

38.00 (31,41.50)

2.133

34.0 (29.60,39.51)

32.0 (30.20,35.0)

31.80 (30.20,36.00)

0.624

Sperm deformity rate (%)

94.95 (94.00,96.00)

94.94 (93.00,96.00)

96.00 (96.00,96.00)#b

5.321*

95.1 (95.00,96.00)

95.92 (94.8,96.0)

95.97 (96.00,96.00)#c

8.263*

PR (%)

37 (26.21,41.22)

28 (15.50,32.80)

20 (19.65,35.05)#a

11.826*

38.20 (26.88,51.20)

26.11 (16.58,33.81)

19.52 (12.62,28.71)#cd

10.286*

Sperm concentration (× 106 /mL)

89.10 (63.33,153.80)

59.20 (31.78,85.60)

45.30 (30.23,61.85)#a

5.162*

67.0 (35.8,105.29)

44.5 (16.80,67.55)

41.2 (20.60,99.17)

4.132

DFI (%)

11.90 (9.20,13.21)

18.63 (16.91,23.55)#a

38.35 (35.00,61.10)#a#b

55.208**

12.34 (8.01,14.59)

22.6 (17.31,25.0)#c

40.6 (35.21,52.87)#c#d

38.26**

  1. **P < 0.01, *P < 0.05; Data in the table are expressed as \({\overline{{x}}}\)  ± S or M (P25, P75).
  2. #a: compared with IVF-I group, #b: compared with IVF-II group, #c: compared with ICSI-I group, #d: compared with ICSI-II group, P < 0.05.
  3. According to DFI levels, IVF group was subdivided into IVF-I group (DFI ≤ 15%), IVF-II group (15% < DFI < 30%), IVF-III group (DFI ≥ 30%); ICSI group was subdivided into ICSI-I group (DFI ≤ 15%), ICSI-II group (15% < DFI < 30%) and ICSI-III group (DFI ≥ 30%).