Figure 2 | Scientific Reports

Figure 2

From: Extra-viral DNA in adeno-associated viral vector preparations induces TLR9-dependent innate immune responses in human plasmacytoid dendritic cells

Figure 2

Comparison of capsid/vg ratios between different AAV8-CMV-eGFP and AAV2-CMV-eGFP vector lots. The capsid/vg ratios derive from absorbance measurements (ELISA) and ddPCR results of (a) eight AAV8 vector lots and (b) four AAV2 vector lots. Dashed lines separate “immunogenic” from “non-immunogenic” AAV vector lots. Bars indicate means and standard deviations of replicates. Statistical significance was determined using unpaired Student t-test.

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