Table 5 Association between circadian rhythm and MCI or cognitive impairment assessed by CMMSE in study population.

From: Association of circadian rhythm with mild cognitive impairment among male pneumoconiosis workers in Hong Kong: a cross-sectional study

 

Community referents

Pneumoconiosis patients

NC/MCI

AOR (95% CI)

NC/MCI

AOR (95% CI)

Percent rhythm a

 ≥ 17.8

61/38

1.00 (ref)

48/28

0.73 (0.36, 1.51)

 < 17.8

71/23

0.48 (0.24, 0.95) **

45/44

1.16 (0.58, 2.31)

Amplitude a

 ≥ 120.8

77/29

1.00 (ref)

50/28

1.13 (0.54, 2.34)

 < 120.8

55/32

1.11 (0.56, 2.21)

43/44

1.62 (0.80, 3.25)

MESOR a

    

 ≥ 254.8

81/32

1.00 (ref)

50/26

1.11 (0.54, 2.27)

 < 254.8

51/29

1.23 (0.61, 2.49)

43/46

1.74 (0.88, 3.44)

Acrophase a

 ≥ 13.8

78/29

1.00 (ref)

42/38

1.89 (0.92, 3.90) *

 < 13.8

54/32

1.05 (0.51, 2.15)

51/34

0.95 (0.45, 2.03)

 

NC/Composite outcomes of MCI plus CI

AOR (95% CI)

NC/Composite outcomes of MCI plus CI

AOR (95% CI)

Percent rhythm a

 ≥ 17.8

61/45

1.00 (ref)

48/43

0.89 (0.46, 1.76)

 < 17.8

71/31

0.52 (0.27, 1.00) **

45/50

1.04 (0.53, 2.05)

Amplitude a

 ≥ 120.8

77/33

1.00 (ref)

50/37

1.26 (0.64, 2.51)

 < 120.8

55/43

1.25 (0.65, 2.41)

43/56

1.66 (0.84, 3.26)

MESOR a

 ≥ 254.8

81/37

1.00 (ref)

50/30

1.09 (0.55, 2.18)

 < 254.8

51/39

1.49 (0.76, 2.89)

43/63

1.99 (1.04, 3.81) **

Acrophase a

 ≥ 13.8

78/35

1.00 (ref)

42/42

1.65 (0.82, 3.33)

 < 13.8

54/41

1.03 (0.52, 2.02)

51/51

1.10 (0.55, 2.23)

  1. aUsing median as the cutoff point.
  2. MCI mild cognitive impairment; CMMSE Cantonese version of the Mini-Mental State Examination; MESOR midline estimating statistic of rhythm; OR odds ratio; CI, confidence interval.
  3. badjusted for age (years) and education (years), marital status, employment, diabetes, hypertension or cardiovascular diseases, sleep medication use, family history of dementia, smoking, alcohol drinking, tea drinker, coffee drinker, anxiety, depression, physical activity, poor sleep (PSQI > 5), waist circumference, and handgrip strength.
  4. ** P < 0.05, * P < 0.1.