Figure 2 | Scientific Reports

Figure 2

From: Coordinated local RNA overexpression of complement induced by interferon gamma in myositis

Figure 2The alt text for this image may have been generated using AI.

Correlation of complement expression with myositis disease activity. The analysis of bulk transcriptomic data showed that the local expression of complement was positively correlated with markers of muscle regeneration (NCAM1, MYOG, PAX7, MYH3, and MYH8) and canonical T-cell and monocyte/macrophage markers (CD3E, CD4, CD8A, CD14, and CD68). In contrast, there was a negative correlation between the expression of complement proteins with markers of mature muscle cells markers (ACTA1, MYH1, and MYH2).

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