Figure 9

Impact of gallic acid on the cerebrum of CdCl2-induced neurotoxic rats (H & E, 200X). Group A (Control rats), Group B (cadmium chloride-treated rats), Group C (CdCl2 + GA-treated rats), Group D (gallic acid-treated rats) (A) Control showing normal granular layer, molecular layer, purkinje cell layer, blood vessels as well as while matter. (B) CdCl2 group showing severe vacuolation of purkinje cell layer, optical empty spaces due to necrosis (arrow), severe separation of purkinje cell layer from granular layer, severe hemorrhage of white matter; (C) CdCl2 + GA group showing vacuolated purkinje cell layer (black arrow), mild separation of purkinje cell layer; (D) GA group reveals normal granular layer, molecular layer, vacuolated purkinje cell layer (black arrow).