Table 1 Summary of the study cohort, demographic and clinical characteristics concerning each group (HC and pwMS). Clinical outcomes are also provided and shown solely for pwMS since such assessments were not carried out on healthy subjects. More information regarding the education demographics can be found in the supplementary material Table A4.
HC (n = 24) | pwMS (n = 102) | p value | |
|---|---|---|---|
Demographics | |||
Age, years, mean (SD) | 42.42 (15.09) | 46.41 (10.44) | \(0.248^a\) |
Sex, n (%) | \(0.085^b\) | ||
Female | 13 (54.16) | 75 (73.53) | |
Male | 11 (45.84) | 27 (26.47) | |
Level of education, n (%) | \(0.233^b\) | ||
Low | 5 (20.83) | 37 (36.27) | |
Middle | 11 (45.83) | 46 (45.09) | |
High | 8 (33.33) | 19 (18.62) | |
MS type, n (%) | n.a. | ||
Relapsing-remitting | n.a. | 61 (59.80) | |
Secondary progressive | n.a. | 30 (29.41) | |
Primary progressive | n.a. | 11 (10.79) | |
Clinical outcomes | |||
EDSS, median (IQR) [n] | n.a. | 3.50 (2.5 – 4.5)[387] | n.a. |
NHPT, median (IQR) [n] | n.a. | 20.40 (18.6 – 22.6) [418] | n.a. |
SDMT, median (IQR) [n] | n.a. | 59.00 (50.0 – 66.0) [419] | n.a. |
