Table 2 Comparison of selected blood parameters in classifying the severity of the main symptoms in canine babesiosis.

From: Haematological indices and immune response profiles in dogs naturally infected and co-infected with Dirofilaria repens and Babesia canis

Symptoms and associated blood parameters ± SEM

Severity class

Reference values

Value of statistics F

P

Class 0 (normal)

Class 1 (mild)

Class 2 (advanced disorder)

Anemia

N = 101

N = 38

N = 31

Erythrocytes (T/l)

6.75 ± 0.79

5.06 ± 0.129

3.39 ± 0.142

5.50–8.50

F2, 169 = 231.75

 < 0.001

Leukocytes (G/l)

8.09 ± 0.562

7.17 ± 0.917

8.12 ± 1.015

6.0–12.0

F2, 169 = 0.40

0.673

Hemoglobin (mmol/l)

9.96 ± -0.122

7.56 ± 0.199

5.21 ± 0.220

9.30–11.8

F2, 169 = 194.04

 < 0.001

Hematocrit (%)

39.51 ± 1.778

26.48 ± 2.899

15.90 ± 3.210

44.0–55.0

F2, 169 = 23.28

 < 0.001

Thrombocytes (g/l)

164.40 ± 14.680

151.23 ± 23.932

28.10 ± 26.497

150.0–500.0

F2, 169 = 10.36

 < 0.001

Hepatic dysfunction

N = 80

N = 48

N = 33

 

AST (U/l)

42.50 ± 10.146

82.53 ± 13.099

140.56 ± 15.798

1.0–76.0

F2, 160 = 13.90

 < 0.001

ALT (U/l)

38.10 ± 7.330

65.49 ± 9.366

124.46 ± 11.413

1.0–80.0

F2, 161 = 20.28

 < 0.001

ALP (U/l)

68.89 ± 6.229

124.67 ± 8.049

249.81 ± 9.960

1.0–141.0

F2, 160 = 117.93

 < 0.001

Renal dysfunction

N = 106

N = 33

N = 24

 

Creatinine (mg/dl)

0.899 ± 0.093

1.003 ± 0.167

1.795 ± 0.195

0.396–1.49

F2, 162 = 8.62

 < 0.001

Serum urea (mg/dl)

31.69 ± 5.180

70.06 ± 9.284

190.40 ± 10.887

19.9–50.0

F2, 162 = 87.02

 < 0.001

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