Table 2 The odds ratios (ORs) and 95% confidence intervals (CIs) of the risk of PTC for creatinine-adjusted UIC among 492 case patients with PTC and 595 control patients with benign thyroid diseases at Samsung Medical Center in South Korea between 2011 and 2016.

From: Association between urinary iodine concentration and the risk of papillary thyroid cancer by sex and age: a case–control study

 

Case

Control

OR (95% CI)

OR (95% CI)*

OR (95% CI)**

Continuous log (creatinine-adjusted UIC)

492

595

1.11 (1.05–1.17)

1.11 (1.05–1.17)

1.11 (1.05–1.18)

Quartiles of creatinine-adjusted UIC

 < 159.3 μg/g Cr

107 (21.7)

149 (25.0)

Ref.

Ref.

Ref.

 159.3–394.3 μg/g Cr

115 (23.4)

149 (25.0)

1.07 (0.76–1.52)

1.10 (0.78–1.57)

1.17 (0.81–1.69)

 394.3–1037.3 μg/g Cr

117 (23.8)

148 (24.9)

1.10 (0.78–1.56)

1.19 (0.83–1.69)

1.14 (0.79–1.66)

 ≥ 1037.3 μg/g Cr

153 (31.1)

149 (25.0)

1.43 (1.02–2.00)

1.47 (1.04–2.06)

1.49 (1.04–2.13)

p-trend

  

0.0376

0.0241

0.0371

  1. PTC papillary thyroid cancer, UIC urinary iodine concentration.
  2. *Adjusted for age and sex.
  3. **Adjusted for age, sex, education level, physical activity, supplement intake, BMI, daily alcohol intake, smoking status, family history of cancer, and history of benign thyroid diseases.
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