Table 1 Anti-tumor efficacy of PZH on Hepa1-6 mouse liver cancer in vivo.
From: Pien Tze Huang regulates phosphorylation of metabolic enzymes in mice of hepatocellular carcinoma
Group | Dose (mg/kg × days), administration | Number (Day 1/22) n = 8 | Body weight (g) Mean ± SD | Tumor weight (g) | ||
|---|---|---|---|---|---|---|
Day 1 | Day 22 | Mean ± SD | TGI% | |||
Control | 0 × 21, po | 8/8 | 19.6 ± 0.6 | 20.9 ± 0.7 | 0.73 ± 0.62 | NA |
Sorafenib | 60 × 21, po | 8/8 | 19.7 ± 0.3 | 19.9 ± 0.8 | 0.06 ± 0.02*** | 92.1 |
PZH | 26 × 21, po | 8/8 | 19.8 ± 0.4 | 19.5 ± 1.7 | 0.30 ± 0.17* | 58.4 |
78 × 21, po | 8/8 | 19.9 ± 0.8 | 19.7 ± 1.0 | 0.28 ± 0.16** | 62.1 | |
234 × 21, po | 8/8 | 19.4 ± 0.7 | 19.4 ± 1.2 | 0.24 ± 0.16** | 67.8 | |
702 × 21, po | 8/8 | 18.7 ± 0.4 | 19.3 ± 1.3 | 0.23 ± 0.11** | 68.6 | |
