Figure 2
From: TRPA1 as a O2 sensor detects microenvironmental hypoxia in the mice anterior cingulate cortex
TRPA1 is unrelated to both excitatory and inhibitory synaptic transmission. (A) Sample trace of sEPSCs. CA: cinnamaldehyde (300 μM). (B–F) Averaged amplitude (B), frequency (C), rise time (D), decay time (E) and area (F) of sEPSCs before and after CA (B; CA − : 12.0 ± 0.9 pA; CA + : 12.0 ± 0.6 pA, t (6) =  − 0.0108, P = 0.496, C; CA − : 2.9 ± 0.6 Hz; CA + : 2.4 ± 0.5 Hz, t (6) = 0.578, P = 0.289, D; CA − : 3.0 ± 0.1 ms; CA + : 3.1 ± 0.1 ms, t (6) =  − 0.75, P = 0.234, E; CA − : 5.7 ± 0.8 ms; CA + : 6.2 ± 0.8 ms, t (6) =  − 0.474, P = 0.322, F; CA − : 70.5 ± 10.2 pA/ms; CA + : 77.2 ± 11.3 pA/ms, t (6) =  − 0.439, P = 0.334, n = 7 neurons/7 mice). (G) Sample trace of sIPSCs. (H–L) Averaged amplitude (H), frequency (I), rise time (J), decay time (K) and area (L) of sIPSCs before and after CA (H; CA − : 14.8 ± 1.8 pA; CA + : 14.7 ± 1.3 pA, t (5) = 0.0478, P = 0.481, I; CA − : 3.1 ± 0.5 Hz; CA + : 3.3 ± 0.6 Hz, t (5) =  − 0.276, P = 0.394, J; CA − : 5.0 ± 0.2 ms; CA + : 5.1 ± 0.1 ms, t (5) =  − 0.55, P = 0.297, K; CA − : 18.3 ± 1.8 ms; CA + : 18.7 ± 1.9 ms, t (5) =  − 0.139, P = 0.446, L; CA − : 276.5 ± 12.5 pA/ms; CA + : 308.9 ± 36.4 pA/ms, t (5) =  − 0.411, P = 0.345, n = 6 neurons/6 mice). All tests for Figure were performed by paired t test. Data are presented as mean ± SEM.
