Table 5 Concordance of cytological analysis with the gold standard according to each device for self-sampling.

Self-sampling devices	Results of the cytological analysis	Conventional sampling					Observed concordance for distinct comparison (italics)* Sensitivity (95% CI) Specificity (95% CI)	Kappa coeficient (95%CI) Weighted Kappa*
Self-sampling devices	Results of the cytological analysis	Negative	Positive	ASC-US or LSIL	ASC-H, AGC or HSIL	Total		Kappa coeficient (95%CI) Weighted Kappa*
Viba-Brush®	Negative	22 (47.8%)	7 (15.2%)	7 (15.2%)	0 (0.0%)	29 (63.0%)	35 (76.1%) 65.0% (40.8%-84.6%) 84.6% (65.1%-95.6%)	0.51 (0.25–0.76)
	Positive	4 (8.7%)	13 (28.3%)	11 (23.9%)	2 (4.3%)	17 (37.0%)	35 (76.1%) 65.0% (40.8%-84.6%) 84.6% (65.1%-95.6%)	0.51 (0.25–0.76)
	ASCUS or LSIL	4 (8.7%)	13 (28.3%)	11 (23.9%)	2 (4.3%)	17 (37.0%)	33 (71.7%)	0.43 (0.19–0.68) 0.46
	ASC-H, AGC or HSIL	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)
	Total	26 (56.5%)	20 (43.5%)	18 (39.1%)	2 (4.4%)	46 (100%)
Mía by XytoTest®	Negative	22 (47.8%)	9 (19.6%)	9 (19.6%)	0 (0.0%)	31 (67.4%)	33 (71.7%) 55.0% (31.5%-76.9%) 84.6% (65.1%-95.6%)	0.41 (0.15–0.67)
	Positive	4 (8.7%)	11 (23.9%)	9 (19.6%)	2 (4.3%)	15 (32.6%)	33 (71.7%) 55.0% (31.5%-76.9%) 84.6% (65.1%-95.6%)	0.41 (0.15–0.67)
	ASCUS or LSIL	4 (8.7%)	10 (21.7%)	8 (17.4%)	2 (4.3%)	14 (30.4%)	30 (65.2%)	0.30 (0.06–0.55) 0.36
	ASC-H, AGC or HSIL	0 (0.0%)	1 (2.2%)	1 (2.2%)	0 (0.0%)	1 (2.2%)
	Total	26 (56.5%)	20 (43.5%)	18 (39.1%)	2 (4.3%)	46 (100%)

Coincidental results between samples are in bold.
ASC-US atypical squamous cells of undetermined significance, LSIL low-grade squamous intraepithelial lesion, ASC-H atypical squamous cells, cannot exclude high-grade intraepithelial lesion, AGC atypical glandular cells, HSIL high-grade squamous intraepithelial lesion, 95% IC 95% confidence interval.
*Firstly, the values corresponding to the comparison between positive and negative Pap smears are shown, later those among three categories (negative; ASC-US and LSIL; ASC-H, AGC and HSIL).

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