Table 2 Degradation kinetic parameters of AA and AA-LLipo.

From: Effect of liposomal formulation of ascorbic acid on corneal permeability

Formulation

t (min)

C0/Ct

log (C0/Ct)

k (1/min)

t1/2 (min)

t90% (min)

AA

240

1.37

0.138

0.0013

523.5

79.3

AA-LLipo

240

1.13

0.052

0.0005

1383.5

209.6

  1. AA, ascorbic acid; LLipo, lyophilized liposomes; C0, concentration of AA at time point zero; Ct, concentration of AA at time point t; k, rate constant of AA degradation process, t1/2, degradation half-life; t90%, shelf-life.
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