Table 3 Secretomic analysis of HBD2-mediated protection from V8 damage in HaCaT cells.
From: A mechanistic evaluation of human beta defensin 2 mediated protection of human skin barrier in vitro
Protein code | Gene | Log2 fold change | p.mod | Protein name |
|---|---|---|---|---|
O15263 | DEFB4A | 13.06 | 0.00 | Beta-defensin 4A |
P02777 | Bovine PF4 | 3.80 | 0.01 | Platelet factor 4 |
Q3MHN5 | Bovine GC | 3.22 | 0.00 | Vitamin D-binding protein |
Q3SZR3 | Bovine ORM1 | 3.16 | 0.00 | Alpha-1-acid glycoprotein |
P07942 | LAMB1 | 2.85 | 0.00 | Laminin subunit beta-1 |
P41361 | Bovine SERPINC1 | 2.75 | 0.00 | Antithrombin-III |
Q0IIK2 | Bovine TF | 2.71 | 0.00 | Serotransferrin |
P02768 | ALB | 2.69 | 0.00 | Albumin |
Q86TE4 | LUZP2 | 2.22 | 0.01 | Leucine zipper protein 2 |
P25774 | CTSS | 2.13 | 0.00 | Cathepsin S |
Q28065 | Bovine C4BPA | 2.06 | 0.01 | C4b-binding protein alpha chain |
Q9H7M9 | C10orf54 | 1.98 | 0.00 | V-type immunoglobulin domain-containing suppressor of T-cell activation |
P17900 | GM2A | 1.98 | 0.01 | Ganglioside GM2 activator |
Q9TRI1 | N/A | 1.96 | 0.01 | Inter-alpha-trypsin inhibitor HC2 component homolog |
Q16778 | H2BC21 | 1.88 | 0.02 | Histone H2B type 2-E |
Q5XQN5 | Bovine KRT5 | 1.85 | 0.00 | Keratin, type II cytoskeletal 5 |
Q5TEC6 | HIST2H3PS2 | 1.85 | 0.01 | Histone H3 |
P02769 | Bovine ALB | 1.70 | 0.00 | Albumin |
Q58D62 | Bovine FETUB | 1.64 | 0.00 | Fetuin-B |
P30519 | HMOX2 | 1.45 | 0.00 | Heme oxygenase 2 |
Q96C19 | EFHD2 | 1.44 | 0.00 | EF-hand domain-containing protein D2 |
P00978 | Bovine AMBP | 1.16 | 0.01 | Protein AMBP |
Q9UII2 | ATPIF1 | − 2.03 | 0.00 | ATPase inhibitor, mitochondrial |
P00439 | PAH | − 3.25 | 0.01 | Phenylalanine-4-hydroxylase |
P63167 | DYNLL1 | − 1.63 | 0.01 | Dynein light chain 1, cytoplasmic |
O60513 | B4GALT4 | − 1.67 | 0.02 | Beta-1,4-galactosyltransferase 4 |
Q15233 | NONO | − 1.61 | 0.00 | Non-POU domain-containing octamer-binding protein |
P14868 | DARS | − 1.48 | 0.01 | Aspartate–tRNA ligase, cytoplasmic |
O95084 | PRSS23 | − 1.48 | 0.02 | Serine protease 23 |
O95425 | SVIL | − 1.33 | 0.00 | Supervillin |
O00170 | AIP | − 1.34 | 0.01 | AH receptor-interacting protein |
P22234 | PAICS | − 1.27 | 0.00 | Multifunctional protein ADE2 |
P00736 | C1R | − 1.27 | 0.01 | Complement C1r subcomponent |
Q5T1M5 | FKBP15 | − 1.30 | 0.05 | FK506-binding protein 15 |
P43243 | MATR3 | − 1.31 | 0.02 | Matrin-3 |
P52895 | AKR1C2 | − 1.31 | 0.04 | Aldo–keto reductase family 1 member C2 |
Q14692 | BMS1 | − 1.14 | 0.01 | Ribosome biogenesis protein BMS1 homolog |
