Table 6 Antimicrobial activity of the examined surfactants in comparison to traditional antibiotics against molds and dermatophyte fungi based on the clear zone diameter (CZDa–c, mm), and minimal lethal concentration (MLC, µg/ml).

From: Evaluation of synthesized biosurfactants as promising corrosion inhibitors and alternative antibacterial and antidermatophytes agents

Treatment

Clear zone diameter (mm) and minimal lethal concentration (MLC μg/ml−1)

C. albicans

Cryptococcus neoforrmans

Trichosporon cataneum

T. rubrum

T. mantigrophytes

CZD*

MLC

CZD*

MLC

CZD*

MLC

CZD*

MLC

CZD*

MLC

Amino acids-based surfactants (100 μg/ml)

 1. SND-Asparagine

36

128

33

128

35

64

36

128

33

128

 2. SND-Histidine

57

16

36

16

48

16

54

16

62

16

 3. SND Tryptophan

45

64

36

64

40

64

43

64

35

64

Conventional antifungal (100 μg/mL)

 Fluconazole

35

nd

37

nd

38

nd

27

nd

35

nd

 Nystatin

30

nd

33

nd

42

nd

28

nd

40

nd

 Ciclopirox

33

nd

31

nd

38

nd

26

nd

45

nd

  1. aThe values are the mean of three samples ± SD.
  2. bInhibition zone was measured as the clear area in the center of agar well.
  3. cnd not determined.