Table 3 Relative risk for composite outcome of CVD and all-cause death according to the CKD causes.

From: Comparison of outcomes of chronic kidney disease based on etiology: a prospective cohort study from KNOW-CKD

Cause of CKD

Cox regression analysis

Cause-specific regression analysis*

HR (95% CI)

P value

HR (95% CI)

P value

Glomerulonephritis

Reference

 

Reference

 

Hypertensive nephropathy

0.97 (0.59–1.59)

0.901

1.24 (0.71–2.15)

0.447

Diabetic nephropathy

1.67 (1.09–2.56)

0.019

2.07 (1.23–3.46)

0.006

Polycystic kidney disease

3.11 (1.59–6.05)

 < 0.001

2.84 (1.36–5.93)

0.006

Cause of CKD

Cox regression analysis

Cause-specific regression analysis*

HR (95% CI)

P value

HR (95% CI)

P value

Hypertensive nephropathy

Reference

 

Reference

 

Diabetic nephropathy

1.82 (1.19–2.79)

0.006

1.73 (1.08–2.78)

0.022

Polycystic kidney disease

1.94 (1.03–3.65)

0.041

1.41 (0.70–2.85)

0.334

 

Cox regression analysis

Cause-specific regression analysis*

HR (95% CI)

P value

HR (95% CI)

P value

Diabetic nephropathy

Reference

 

Reference

 

Polycystic kidney disease

1.84 (0.93–3.63)

0.079

1.74 (0.79, 3.84)

0.169

  1. *For the composite outcome of CVD and death, cause-specific regression analysis was conducted as a competing risk analysis using the kidney failure as competing event considering the undetected CVD after starting kidney replacement therapy.
  2. CI, confidence interval; CKD, chronic kidney disease; CVD, cardiovascular disease; HR; hazard ratio.
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