Figure 10

Simulations of 2D and 3D 8-sample pooling strategies. (a) Similar sample sets to those in Fig. 7 were created with 1,024 total samples and positive samples randomly introduced at 1–10% positivity rates. (b, c) The number of confirmed and potential positives, respectively. Above 8% prevalence no confirmed positive samples can be determined by 2D pooling, while 3D pooling identified significant numbers of known positives even at 10% prevalence. (d) As prevalence surpasses 5%, the total number of tests for each strategy equilibrates.