Table 1 CD signal intensities at 208 nm and 222 nm for the three Aβ variants Aβ40, Aβ40(NoHis), and Aβ(4–40), as a function of added Ni(II) acetate.
Wavelength (nm) | 0 µM Ni(II) | 2 µM Ni(II) | 4 µM Ni(II) | 16 µM Ni(II) | 56 µM Ni(II) | 156 µM Ni(II) | 256 µM Ni(II) | |
|---|---|---|---|---|---|---|---|---|
Aβ40 | 208 | − 11,131 | − 10,808 | − 10,557 | − 9928 | − 9515 | − 9064 | − 9025 |
222 | − 7793 | − 7925 | − 8074 | − 8241 | − 8339 | − 8012 | − 8114 | |
222/208 | 0.700 | 0.733 | 0.765 | 0.830 | 0.8764 | 0.884 | 0.899 | |
Aβ40(NoHis) | 208 | − 14,062.7 | − 13,979 | − 14,112.3 | − 13,919.9 | − 13,962.9 | 19,802.9 | 13,725.2 |
222 | − 11,184.4 | − 11,100.6 | − 11,249.3 | − 11,138.9 | − 11,172.6 | − 11,149.8 | − 11,039.3 | |
222/208 | 0.7953 | 0.7941 | 0.7971 | 0.8002 | 0.8002 | 0.8078 | 0.8043 | |
Aβ(4–40) | 208 | − 5335.7 | − 5265.9 | − 5258.7 | − 4876.8 | − 4338.2 | − 4235.2 | − 4150.7 |
222 | − 3978.0 | − 3989.9 | − 4193.3 | − 4302.0 | − 4205.2 | − 4176.1 | 4268.9 | |
222/208 | 0.746 | 0.758 | 0.797 | 0.882 | 0.969 | 0.986 | 1.028 |
