Table 1 In vitro antioxidant activity of nitrones QNs 1–6a.
Standards/nitrones | Clog P | LOX (%)/IC50 | ILPO (%) | .OH (%) | ABTS+ (%) |
|---|---|---|---|---|---|
NDGA | nd | 0.45 μΜ | nd | nd | nd |
Trolox | nd | nd | 93 | 73 | 91 |
PBN | 3.02 | 23% | 11 | na | 5 |
QN1 | nd | nd | nd | nd | nd |
QN2 | 2.74 | na | 32 | 71 | 20 |
QN3 | 2.08 | na | 75 | 90 | 65 |
QN4 | 2.61 | 52.5 μΜ | 60 | na | 77.4 |
QN5 | 2.49 | 5 μΜ | 81.5 | 83.3 | 8 |
QN6 | 3.03 | 26% | 45 | 22 | 81.4 |
