Figure 4

Effects of PDL as quantitatively assessed by X-ray imaging in the MIA induced OA mice model. (A) Representative radiographs of the left knee (L) in the sham (sham), sodium iodoacetate (MIA), MIA + indomethacin and PDL groups after day 28 of treatment. Anteroposterior (a, b, c, d, and e) and lateral (f, g, h, i, and j) radiographs of the knee joint in mice. (B) Results of KL grade scoring for each group. The data were present as mean ± SD. (n = 5, ####p < 0.0001 compared with the Sham group. **p < 0.01, ****p < 0.0001 compared with the MIA group).