Table 4 The comparison of the effect among screening and no screening strategies.
From: Cost-effectiveness evaluation of risk-based breast cancer screening in Urban Hebei Province
Variables | Frequency | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
No screening | Ultrasound | Mammography | Combined | |||||||
Annual | Biennial | Triennial | Annual | Biennial | Triennial | Annual | Biennial | Triennial | ||
Summary of morbidity and mortality at the end of the 45 years in each screening program | ||||||||||
DCIS + I stage | 282 | 452 | 367 | 331 | 517 | 400 | 352 | 541 | 413 | 360 |
IV stage | 163 | 140 | 149 | 149 | 135 | 147 | 147 | 133 | 146 | 146 |
Cancer cases | 648 | 814 | 766 | 747 | 852 | 785 | 761 | 866 | 791 | 765 |
Total deaths | 71,776 | 71,609 | 71,659 | 71,676 | 71,573 | 71,640 | 71,663 | 71,558 | 71,632 | 71,658 |
Early diagnosis rate (%) | 43.52 | 55.53 | 47.91 | 44.31 | 60.68 | 50.96 | 46.25 | 62.47 | 52.21 | 47.06 |
Proportion of advanced cancers (%) | 25.15 | 17.20 | 19.45 | 19.95 | 15.85 | 18.73 | 19.32 | 15.36 | 18.46 | 19.08 |
Morbidity and mortality of each screening group (person year) | ||||||||||
DCIS | 8213 | 15,710 | 10,739 | 8846 | 19,483 | 12 677 | 10 085 | 20,947 | 13,428 | 10,565 |
I stage | 13,808 | 17,650 | 17,215 | 17,037 | 17,985 | 17 394 | 17 148 | 18,119 | 17,462 | 17,193 |
II stage | 7829 | 9268 | 11,399 | 12,206 | 7653 | 10 568 | 11 673 | 7024 | 10,248 | 11,471 |
III stage | 7669 | 6519 | 7487 | 7852 | 5779 | 7111 | 7609 | 5496 | 6964 | 7518 |
IV stage | 11,793 | 8891 | 9549 | 9794 | 8395 | 9288 | 9630 | 8203 | 9193 | 9567 |
No cancer deaths | 1,666,219 | 1,675,473 | 1,674,074 | 1,673,479 | 1,676,580 | 1,674,663 | 1,673,844 | 1,677,008 | 1,674,889 | 1,673,989 |
Cancer deaths | 61,270 | 43,597 | 46,648 | 47,898 | 41,230 | 45,402 | 47,112 | 40,311 | 44,922 | 46,813 |
Total deaths | 1,727,489 | 1,719,070 | 1,720,722 | 1,721,377 | 1,717,810 | 1,720,065 | 1,720,956 | 1,717,319 | 1,719,811 | 1,720,802 |
Development of each screening group in the next 45 years | ||||||||||
Early-stage cases | 22,021 | 33,360 | 27,954 | 25,883 | 37,468 | 30,071 | 27,233 | 39,066 | 30,890 | 27,758 |
Early diagnosis rate increased (%) | – | 51.49 | 26.94 | 17.54 | 70.15 | 36.56 | 23.67 | 77.40 | 40.28 | 26.05 |
IV stage cases | 11,793 | 8891 | 9549 | 9794 | 8395 | 9288 | 9630 | 8203 | 9193 | 9567 |
IV stage incidence decreased (%) | – | 24.61 | 19.03 | 16.95 | 28.81 | 21.24 | 18.34 | 30.44 | 22.05 | 18.88 |
Breast cancer deaths | 61,270 | 43,597 | 46,648 | 47,898 | 41,230 | 45,402 | 47,112 | 40,311 | 44,922 | 46,813 |
Breast cancer mortality decreased (%) | – | 28.84 | 23.86 | 21.82 | 32.71 | 25.90 | 23.11 | 34.21 | 26.68 | 23.60 |
