Figure 4 | Scientific Reports

Figure 4

From: Sodium benzoate attenuates 2,8-dihydroxyadenine nephropathy by inhibiting monocyte/macrophage TNF-α expression

Figure 4The alternative text for this image may have been generated using AI.

SB reduces the phosphorylation of JNK, ERK, and NF-κB p65 in the kidneys of AdCKD mice. (a) Immunoblots of the respective groups are shown. Band intensities of (b) phopho-p38 MAPK (p-p38 MAPK), (c) phospho-JNK (p-JNK), (d) phospho-ERK (p-ERK), (e) phospho-Akt (p-Akt), and (f) phospho-NF-κB p65 (p-NF-κB p65) were quantified and adjusted to the intensities of the internal control molecule β-actin (n = 4–10). Mice in the AdCKD + SB group showed decreased levels of p-JNK, p-ERK, and p-NF-κB p65 compared with mice in the AdCKD group. *p < 0.05; **p < 0.01; ***p < 0.001; ns, not significant. Each bar represents mean ± SEM. SB, sodium benzoate.

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