Table 2 The study protocol for each group.

Fed under normal conditions

Always

2 weeks

2 weeks

11 days

1 week

No

No

Fed under altitude conditions

No

No

No

3 days

1 week

2 weeks

2 weeks

Inhibitor intraperitoneal injection

No

No

No

No

No

No

Yes

Treadmill load exercise

No

Yes^#

Yes*

Yes*

Yes*

Yes*

Yes*

Recorded exhaustive time^a

No

Yes

Yes

Yes

Yes

Yes

Yes

Western blotting^b

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Immunohistochemical detection^c

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Neuropathological evaluation^c

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Brain lactate content determination^d

Yes

Yes

Yes

Yes

Yes

Yes

Yes