Table 3 Topological parameters of resveratrol anti-fatigue core target genes.

From: Exploring the mechanism of anti-fatigue of resveratrol based on network pharmacology and molecular docking, and in vitro studies

Target

Moderate centrality

Compact centrality

Mediation centrality

Clustering coefficient

STAT3

0.1016

0.5116

0.1016

0.2710

TP53

0.1108

0.5000

0.1108

0.2389

PIK3R1

0.07581

0.5176

0.1164

0.2792

AKT1

0.1164

0.5207

0.0758

0.2906

SRC

0.0359

0.4835

0.0666

0.3297

ESR1

0.0666

0.4862

0.0359

0.3659

PIK3CA

0.04163

0.5087

0.04163

0.3636

MAPK1

0.0479

0.4862

0.0479

0.2814

PTPN11

0.0362

0.4862

0.03617

0.3952

CTNNB1

0.0176

0.4706

0.0625

0.2865