Figure 2 | Scientific Reports

Figure 2

From: Analgesic effects of a highly selective mPGES-1 inhibitor

Figure 2

Anti-inflammatory and analgesic effects of UK4b on CFA-induced knee joint arthritis in rats (n = 10 for each group). CFA was injected to the knee joint on Day 0. UK4b (5 or 10Β mg/kg) or vehicle (control) was injected (IP) daily on Days 3 to 6. (A) PWL data measured on Days 0 to 7. (B) Arthritis score (mean spontaneous pain rating) measured on Days 0 to 8, 10, and 12. Statistical significance (two-way ANOVA): *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

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