Table 2 Comparison of retinal layer thicknesses in preterm patients with a history of retinopathy of prematurity with treatment, spontaneously regressed, and full-term healthy controls.
Variables | tROP patients (n = 38) | srROP Patients (n = 40) | Healthy controls (n = 43) | tROP vs. HC | srROP vs. HC | tROP vs. srROP | Adjusted p valuea |
|---|---|---|---|---|---|---|---|
pRNFL thickness (μm) | |||||||
Global | 106.69 ± 14.88 | 91.62 ± 12.76 | 102.41 ± 10.29 | 4.14 (2.83) | − 11.26 (2.85) | − 15.40 (2.91) | < 0.0001 |
Superior | 110.68 ± 20.3 | 117.43 ± 21.7 | 125.67 ± 18.9 | − 15.01 (4.54) p = 0.0304 | − 8.31 (4.57) | 6.70 (4.66) | 0.0052 |
Inferior | 131.53 ± 34.8 | 116.75 ± 22.9 | 134.95 ± 19.5 | − 4.06 (5.80) | − 20.33 (5.83) p = 0.0168 | − 16.27 (5.95) | 0.0018 |
Nasal | 55.87 ± 12.08 | 57.98 ± 10.8 | 66.58 ± 13.6 | − 11.00 (2.71) p = 0.0024 | − 9.58 (2.72) p = 0.0152 | 1.42 (2.78) | 0.0001 |
Temporal | 128.68 ± 28.7 | 74.33 ± 18.3 | 82.42 ± 14.9 | 46.65 (4.71) p < 0.0001 | − 6.82 (4.73) | − 53.46 (4.83) p < 0.0001 | < 0.0001 |
GCIPL thickness (μm) | |||||||
Global | 68.09 ± 21.05 | 77.54 ± 8.41 | 83.64 ± 5.34 | − 16.01 (3.56) | − 6.84 (3.53) | 9.17 (3.44) | 0.0001 |
Superior | 65.39 ± 27.26 | 78.56 ± 8.45 | 83.97 ± 6.32 | − 19.11 (4.45) p = 0.0008 | − 6.26 (4.42) | 12.85 (4.31) | 0.0002 |
Inferior | 59.00 ± 27.23 | 74.69 ± 12.63 | 81.90 ± 5.48 | − 23.45 (4.67) p < 0.0001 | − 8.09 (4.64) | 15.35 (4.52) p = 0.0248 | < 0.0001 |
Nasal | 68.73 ± 21.17 | 79.69 ± 9.59 | 85.29 ± 6.14 | − 16.97 (3.68) p < 0.0001 | − 6.27 (3.65) | 10.71 (3.56) | 0.0001 |
Temporal | 79.20 ± 20.59 | 77.23 ± 7.01 | 83.17 ± 5.03 | − 4.26 (3.41) | − 6.39 (3.38) | − 2.13 (3.30) | 0.1673 |
