Figure 2 | Scientific Reports

Figure 2

From: Germline VWF/MPRIP and somatoplasm FGA variants synergically confer susceptibility to non-traumatic osteonecrosis of the femoral head

Figure 2

PPI network and functional modules. (A) PPI network. left: 436 nodes and 2888 edges. The outer circle represents interaction proteins whereas the inner circle represents candidate genes. right: Among 22 candidate genes, FGA and VWF have the highest Degree, and interact with MPRIP. The color indicates a change in Degree. The darker color indicates greater Degree and more important function node in the network (B) VWF, MPRIP and FGA belong to the same function module. yellow, red and blue represents germline mutation, somatic mutation, and interaction protein, respectively.

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