Figure 3 | Scientific Reports

Figure 3

From: Akkermansia muciniphila exerts immunomodulatory and anti-inflammatory effects on gliadin-stimulated THP-1 derived macrophages

Figure 3

A. muciniphila modulates immune-regulatory cytokines. (A) The qRT-PCR analysis represented a significant reduction of IL-6 expression in the AK (MOI = 100) + Gli group compared to the Gli (gliadin) group. (B) Relative expression of TGF-β. (C) Relative expression of IL-10. (D) TNF-α and (E) IL-10 production by MQs with various treatments. Results were analyzed by One-way ANOVA (Triplicate assays) (*p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001). AK, A. Muciniphila; Gli, gliadin; LPS, lipopolysaccharide; MOI, the multiplicity of infection.

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