Table 1 Characteristics of patients with DED and patients without DED.

From: Pediatric chronic graft-versus-host disease-related dry eye disease and the diagnostic association of potential clinical findings

 

Total

DED

non-DED

p value

(n = 26)

(n = 11)

(n = 15)

Male, n (%)

13 (50)

5 (45.5)

8 (53.5)

0.64

Mean age at transplantation, y (SD)

8.7 (4.6)

10.2 (4.6)

7.6 (4.1)

0.17

Median follow-up time, y, (IQR)

3.6 (1.3–10.2)

3.7 (1.2–10.6)

3.3 (1.7–9.7)

0.65

Related donor, n (%)

15 (57.7)

5 (45.5)

10 (66.7)

0.26

Acute GVHD ( +), n (%)

18 (69.2)

9 (81.8)

9 (60.0)

0.22

Chronic GVHD ( +), n (%)

16 (61.5)

9 (81.8)

7 (46.7)

0.06

Disease at transplantation, n (%)

Acute lymphoid leukemia

5 (19.2)

3 (27.2)

2 (13.3)

0.37

Aplastic anemia

4 (15.3)

0 (0)

4 (26.7)

0.06

Juvenile myelomonocytic leukemia

3 (11.5)

0 (0)

3 (20.0)

0.11

Myelodysplastic syndromes

2 (7.7)

0 (0)

2 (13.3)

0.20

Chronic myelogenous leukemia

2 (7.7)

1 (9.0)

1 (6.7)

0.81

Neuroblastoma

2 (7.7)

1 (9.0)

1 (6.7)

0.81

Fanconi anemia

2 (7.7)

2 (18.1)

0 (0)

0.08

Acute myeloid leukemia

2 (7.7)

2 (18.1)

0 (0)

0.08

Other

4 (15.3)

2 (18.1)

2 (13.3)

0.73

Ophthalmic symptoms ( +), n (%)

3 (11.5)

3 (27.2)

0 (0)

0.03

  1. DED dry eye disease; GVHD graft-versus-host-disease; SD standard deviation; IQR interquartile range; ( +) positive.