Table 1 Characteristics of patients with DED and patients without DED.
Total | DED | non-DED | p value | |
|---|---|---|---|---|
(n = 26) | (n = 11) | (n = 15) | ||
Male, n (%) | 13 (50) | 5 (45.5) | 8 (53.5) | 0.64 |
Mean age at transplantation, y (SD) | 8.7 (4.6) | 10.2 (4.6) | 7.6 (4.1) | 0.17 |
Median follow-up time, y, (IQR) | 3.6 (1.3–10.2) | 3.7 (1.2–10.6) | 3.3 (1.7–9.7) | 0.65 |
Related donor, n (%) | 15 (57.7) | 5 (45.5) | 10 (66.7) | 0.26 |
Acute GVHD ( +), n (%) | 18 (69.2) | 9 (81.8) | 9 (60.0) | 0.22 |
Chronic GVHD ( +), n (%) | 16 (61.5) | 9 (81.8) | 7 (46.7) | 0.06 |
Disease at transplantation, n (%) | ||||
Acute lymphoid leukemia | 5 (19.2) | 3 (27.2) | 2 (13.3) | 0.37 |
Aplastic anemia | 4 (15.3) | 0 (0) | 4 (26.7) | 0.06 |
Juvenile myelomonocytic leukemia | 3 (11.5) | 0 (0) | 3 (20.0) | 0.11 |
Myelodysplastic syndromes | 2 (7.7) | 0 (0) | 2 (13.3) | 0.20 |
Chronic myelogenous leukemia | 2 (7.7) | 1 (9.0) | 1 (6.7) | 0.81 |
Neuroblastoma | 2 (7.7) | 1 (9.0) | 1 (6.7) | 0.81 |
Fanconi anemia | 2 (7.7) | 2 (18.1) | 0 (0) | 0.08 |
Acute myeloid leukemia | 2 (7.7) | 2 (18.1) | 0 (0) | 0.08 |
Other | 4 (15.3) | 2 (18.1) | 2 (13.3) | 0.73 |
Ophthalmic symptoms ( +), n (%) | 3 (11.5) | 3 (27.2) | 0 (0) | 0.03 |