Figure 3 | Scientific Reports

Figure 3

From: Mechanistic insight into the protective effects of fisetin against arsenic-induced reproductive toxicity in male rats

Figure 3

Histoarchitectural changes caused by arsenic and FIS in testes (H&E, 200 ×). (A) Control exhibiting thickened epithelium and proper spermatogenesis, (B) Arsenic-intoxicated rats showing increased interstitial spaces and degenerated epithelial layer in addition to the luminal space with lowered germ cells number, (C) Arsenic + FIS-treated rats presenting restoration in epithelial state, a little reduction in interstitial spaces, and luminal portion with higher number of sperm cells compared with arsenic-administered rats, (D) FIS-treated rats showing compact epithelial layer, very less interstitial spaces, and luminal area containing high number of spermatogenic cells. TA tunica albuginea, EH epithelium height, TL tubule luminal area, IS interstitium, ST spermatids, PS primary spermatocyte, SG spermatogonia, SS secondary spermatocytes.

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