Table 2 Disease binary classification based on individual brain structures.
From: Comparative validation of AI and non-AI methods in MRI volumetry to diagnose Parkinsonian syndromes
Case | Midbrain | Pons | Midbrain/pons | V3 | Caudate | Putamen | Pallidum | |
|---|---|---|---|---|---|---|---|---|
Normal vs. PSP | V-Net | \({0.73\pm 0.06}\) | \({0.69\pm 0.03}^*\) | \({0.65\pm 0.08}\) | \({0.83\pm 0.09}^*\) | \({0.54\pm 0.04}\) | \({0.74\pm 0.01}^*\) | \({0.78\pm 0.05}^*\) |
UNETR | \({0.69\pm 0.06}\) | \({0.64\pm 0.05}^*\) | \(0.60\pm 0.07\) | \({0.84\pm 0.08}^*\) | \({0.57\pm 0.03}\) | \({0.69\pm 0.03}^*\) | \({0.76\pm 0.05}\) | |
FS | \(0.70\pm 0.06\) | \(\mathbf {0.89\pm 0.05}\) | \(0.65\pm 0.08\) | \(0.82\pm 0.02\) | \(0.56\pm 0.06\) | \(0.62\pm 0.09\) | \(0.72\pm 0.11\) | |
Normal vs. MSA-P | V-Net | \({0.63\pm 0.05}\) | \({0.60\pm 0.05}\) | \(\mathbf {0.73\pm 0.03}\) | \(\mathbf {0.73\pm 0.03}\) | \({0.61\pm 0.02}\) | \(\mathbf {0.73\pm 0.03}\) | \({0.67\pm 0.10}\) |
UNETR | \({0.61\pm 0.05}\) | \({0.67\pm 0.06}\) | \({0.70\pm 0.05}\) | \({0.70\pm 0.03}\) | \({0.59\pm 0.03}\) | \(\mathbf {0.73\pm 0.03}\) | \(0.65\pm 0.09\) | |
FS | \(0.64\pm 0.04\) | \(0.65\pm 0.04\) | \(0.70\pm 0.05\) | \(\mathbf {0.73\pm 0.03}\) | \(0.60\pm 0.06\) | \(0.70\pm 0.03\) | \(0.66\pm 0.08\) | |
Normal vs. MSA-C | V-Net | \({0.76\pm 0.11}\) | \({0.90\pm 0.04}\) | \(\mathbf {0.91}\pm \mathbf {0.02}\) | \({0.56\pm 0.02}\) | \({0.61\pm 0.01}\) | \({0.65\pm 0.11}\) | \({0.66\pm 0.09}\) |
UNETR | \({0.73\pm 0.08}\) | \({0.86\pm 0.06}\) | \({0.81\pm 0.15}\) | \({0.58\pm 0.01}^*\) | \(0.57\pm 0.04\) | \(0.62\pm 0.10\) | \({0.66\pm 0.07}\) | |
FS | \(0.76\pm 0.10\) | \(0.90\pm 0.04\) | \(\mathbf {0.91\pm 0.02}\) | \(0.56\pm 0.01\) | \(0.62\pm 0.10\) | \(0.65\pm 0.10\) | \(0.71\pm 0.09\) | |
Normal vs. PD | V-Net | \({0.55\pm 0.02}\) | \({0.53\pm 0.02}\) | \({0.57\pm 0.04}\) | \({0.61\pm 0.07}\) | \({0.57\pm 0.02}\) | \({0.55\pm 0.03}\) | \({0.56\pm 0.02}\) |
UNETR | \({0.58\pm 0.03}\) | \(0.55\pm 0.03\) | \(0.53\pm 0.04\) | \(\mathbf {0.63\pm 0.06}\) | \(0.55\pm 0.04\) | \(0.54\pm 0.05\) | \(0.54\pm 0.03\) | |
FS | \(0.56\pm 0.02\) | \(0.52\pm 0.01\) | \(0.57\pm 0.04\) | \(0.61\pm 0.08\) | \(0.54\pm 0.02\) | \(0.57\pm 0.01\) | \(0.54\pm 0.02\) | |
PD vs. PSP | V-Net | \({0.71\pm 0.07}\) | \({0.67\pm 0.03}\) | \({0.58\pm 0.07}\) | \({0.74\pm 0.09}\) | \({0.54\pm 0.02}\) | \({0.67\pm 0.03}\) | \(\mathbf {0.75\pm 0.03}\) |
UNETR | \(0.67\pm 0.09\) | \(0.63\pm 0.07\) | \(0.57\pm 0.08\) | \({0.72\pm 0.10}\) | \({0.52\pm 0.01}\) | \({0.63\pm 0.01}\) | \({0.72\pm 0.05}\) | |
FS | \(0.69\pm 0.06\) | \(0.65\pm 0.04\) | \(0.58\pm 0.07\) | \(0.74\pm 0.11\) | \(0.52\pm 0.01\) | \(0.62\pm 0.03\) | \(0.71\pm 0.08\) | |
PD vs. MSA-P | V-Net | \({0.59\pm 0.07}\) | \({0.67\pm 0.02}\) | \({0.58\pm 0.06}\) | \({0.65\pm 0.08}\) | \({0.58\pm 0.02}\) | \({0.67\pm 0.01}^*\) | \({0.65\pm 0.07}\) |
UNETR | \({0.56\pm 0.02}\) | \({0.64\pm 0.02}\) | \({0.67\pm 0.04}^*\) | \(0.59\pm 0.05\) | \({0.61\pm 0.03}\) | \({0.66\pm 0.01}^*\) | \({0.63\pm 0.05}\) | |
FS | \(0.59\pm 0.03\) | \(0.66\pm 0.02\) | \(0.58\pm 0.06\) | \(0.65\pm 0.08\) | \(0.59\pm 0.04\) | \(\mathbf {0.69\pm 0.04}\) | \(0.66\pm 0.07\) | |
PD vs. MSA-C | V-Net | \({0.74\pm 0.06}\) | \({0.90\pm 0.03}\) | \(\mathbf {0.94\pm 0.02}\) | \({0.56\pm 0.08}\) | \({0.59\pm 0.06}\) | \({0.50\pm 0.07}\) | \({0.64\pm 0.06}\) |
UNETR | \({0.69\pm 0.02}\) | \({0.82\pm 0.11}\) | \({0.81\pm 0.16}\) | \(0.56\pm 0.08\) | \({0.58\pm 0.01}\) | \(0.57\pm 0.05\) | \({0.62\pm 0.05}\) | |
FS | \(0.71\pm 0.06\) | \(0.90\pm 0.03\) | \(\mathbf {0.94\pm 0.02}\) | \(0.57\pm 0.08\) | \(0.59\pm 0.06\) | \(0.59\pm 0.08\) | \(0.69\pm 0.10\) | |
