Table 1 Daily mean, amplitude of diurnal variation, acrophase, Rayleigh test results and repeated measures ANOVA (analysis of variance) outcomes for the choriocapillaris and deep choroidal OCT-A indices of the sub-foveal, sub-parafoveal and sub-perifoveal regions for all participants. *Diurnal amplitude is also expressed as the percentage of the daily mean value. †P values from repeated measures ANOVA for time of day, refractive error, and time by refractive error. P < 0.05 is highlighted in bold. SD standard deviation, CD circular deviation, df degree of freedom.
OCT-A indices | Sub-macular regions | Daily mean | Diurnal amplitude | Acrophase peak time | Rayleigh test | Repeated measures ANOVA | ||
|---|---|---|---|---|---|---|---|---|
Time of day (df = 6, 258) | Time by refractive error (df = 6, 252) | Refractive error (df = 1, 42) | ||||||
Mean ± SD | Mean ± SD *(%) | Time ± CD (h) | Rayleigh’s r, P value | †P value | ||||
Choriocapillaris-flow deficit number | Sub-fovea | 272.33 ± 42.88 | 24.14 ± 15.13 (8.86%) | 2:23 AM ± 4.20 | 0.44, < 0.001 | 0.02 | 0.99 | 0.002 |
Choriocapillaris-average flow deficit size (µm2) | 399.26 ± 189.52 | 71.55 ± 80.67 (17.89%) | 2:52 AM ± 4.50 | 0.31, 0.010 | 0.04 | 0.06 | 0.009 | |
Choriocapillaris-flow deficit density (%) | 14.15 ± 6.72 | 2.64 ± 1.68 (18.66%) | 3:00 AM ± 4.00 | 0.46, < 0.001 | < 0.001 | 0.02 | 0.001 | |
Deep choroidal-perfusion density (%) | 57.22 ± 4.41 | 1.53 ± 0.79 (2.67%) | 4:48 AM ± 4.54 | 0.29, 0.034 | 0.06 | 0.41 | 0.57 | |
Choriocapillaris-flow deficit number | Sub-parafovea | 1446.76 ± 220.77 | 108.66 ± 71.79 (7.51%) | 2:19 AM ± 4.19 | 0.40, < 0.001 | 0.006 | 0.92 | 0.001 |
Choriocapillaris-average flow deficit size (µm2) | 374.05 ± 172.29 | 51.85 ± 55.97 (13.86%) | 2:23 AM ± 4.29 | 0.37, 0.001 | 0.08 | 0.04 | 0.001 | |
Choriocapillaris-flow deficit density (%) | 13.50 ± 6.44 | 2.56 ± 3.97 (18.96%) | 4:33 AM ± 4.69 | 0.46, < 0.001 | 0.002 | 0.03 | 0.001 | |
Deep choroidal-perfusion density (%) | 53.98 ± 3.68 | 1.51 ± 0.91 (2.80%) | 5:05 AM ± 4.29 | 0.37, 0.003 | 0.02 | 0.03 | 0.35 | |
Choriocapillaris-flow deficit number | Sub-perifovea | 2499.66 ± 426.47 | 227.03 ± 127.86 (9.08%) | 4:43 AM ± 4.73 | 0.23, 0.090 | 0.08 | 0.54 | < 0.001 |
Choriocapillaris-average flow deficit size (µm2) | 608.53 ± 275.43 | 98.66 ± 105.02 (16.21%) | 6:13 AM ± 4.78 | 0.22, 0.090 | 0.11 | 0.38 | 0.001 | |
Choriocapillaris-flow deficit density (%) | 10.70 ± 5.92 | 2.39 ± 2.11 (22.34%) | 4:25 AM ± 4.65 | 0.27, 0.048 | 0.03 | 0.48 | 0.002 | |
Deep choroidal-perfusion density (%) | 51.57 ± 2.79 | 1.45 ± 0.93 (2.81%) | 3:12 AM ± 4.32 | 0.36, 0.003 | < 0.001 | 0.20 | 0.21 | |
