Table 4 Univariable and multivariable analyses of risk factors for postoperative acute kidney injury.

From: Intraoperative mean arterial pressure and acute kidney injury after robot-assisted laparoscopic prostatectomy: a retrospective study

 

Univariable

Multivariable

OR (95% CI)

P value

OR (95% CI)

P value

ARV-MAP, 10 mmHg/min increase

2.94 (0.32–27.1)

0.342

  

SD-MAP, 10 mmHg increase

1.58 (0.38–6.63)

0.534

  

TWA-MAP, 10 mmHg increase

1.55 (0.81–2.99)

0.189

1.71 (0.61–4.77)

0.310

AUT-65 mmHg, 50 mmHg × min increase

0.70 (0.44–1.13)

0.146

0.62 (0.35–1.09)

0.095

AAT-120 mmHg, 50 mmHg × min increase

1.11 (0.76–1.61)

0.600

  

Age, 10 y increase

1.29 (0.65–2.55)

0.465

  

Body mass index, 5 kg/m2 increase

2.05 (0.94–4.49)

0.073

1.87 (0.68–5.09)

0.224

ASA physical status ≥ III (referent I & II)

6.13 (2.16–17.4)

0.001

4.97 (1.51–16.3)

0.008

Comorbidities

  

 Hypertension

2.69 (0.88–8.25)

0.084

  

 Diabetes mellitus

3.06 (1.16–8.05)

0.023

  

 Coronary artery disease

4.26 (1.35–13.5)

0.014

  

 COPD

1.28 (0.29–5.70)

0.743

  

 Atrial fibrillation

5.90 (1.60–21.8)

0.008

  

 Chronic kidney disease

4.69 (1.01–21.9)

0.049

  

Preoperative medication

 β-blocker

1.28 (0.29–5.70)

0.743

  

 Calcium channel blocker

1.01 (0.37–2.71)

0.990

  

 ACEI or ARB

3.58 (1.26–10.14)

0.016

2.79 (0.78–9.96)

0.115

 Diuretics

3.37 (1.17–9.71)

0.025

1.67 (0.47–5.93)

0.432

Preoperative MAP, 10 mmHg increase

0.92 (0.53–1.62)

0.777

  

Preoperative laboratory values

 Hematocrit, 3% increase

1.18 (0.79–1.77)

0.427

  

 Serum albumin, 1 g/dL increase

0.62 (0.12–3.30)

0.571

  

 eGFR, 10 mL/min/1.73 m2 increase

0.67 (0.50–0.89)

0.007

0.75 (0.54–1.05)

0.094

 Serum sodium, 5 mmol/L increase

1.15 (0.37–3.59)

0.814

  

Trendelenburg position time, 10 min increase

1.17 (1.05–1.29)

0.004

1.01 (0.80–1.28)

0.936

Anesthesia time, 30 min increase

1.28 (0.95–1.73)

0.107

  

Fluid intake, 100 mL increase

1.14 (1.04–1.26)

0.007

1.27 (0.99–1.62)

0.058

Urine output, 50 mL increase

0.74 (0.56–0.99)

0.039

0.61 (0.42–0.89)

0.009

Blood loss, 100 mL increase

1.13 (1.00–1.28)

0.059

0.77 (0.58–1.02)

0.065

Transfusion of red blood cells, yes

30.4 (4.75–194)

 < .001

22.4 (0.51–988)

0.107

Administered dose of remifentanil, 100 µg increase

1.29 (1.05–1.60)

0.016

1.13 (0.77–1.66)

0.522

Administered dose of ephedrine, 4 mg increase

0.91 (0.67–1.23)

0.526

  

Use of NE or phenyl, yes

0.84 (0.11–6.43)

0.865

  
  1. OR odds ratio, CI confidence interval, ARV average real variability, SD standard deviation, TWA time-weighted average, MAP mean arterial pressure, AUT area under threshold, AAT area above threshold, ASA American Society of Anesthesiologists, COPD chronic obstructive pulmonary diseas, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, eGFR estimated glomerular filtration rate, NE norepinephrine, Phenyl phenylephrine.
Back to article page