Table 1 Patient characteristics.
Characteristic | Total patients (%) N = 157 |
|---|---|
Age | |
 Median (range), years | 66 (61–75) |
  < 65 years | 67 (42.7%) |
  > 65 years | 90 (57.5%) |
Sex | |
 Female | 96 (61.1%) |
 Male | 61 (38.9%) |
Brain metastasis | 68 (43.3%) |
Stage | |
 3B | 8 (5.1%) |
 4A | 40 (25.5%) |
 4B | 109 (69.4) |
Tumor size | |
 < 3 cm | 32 (20.4%) |
 ≥ 3 cm | 125 (79.6%) |
Nodal stage | |
 N0-2 | 48 (30.6%) |
 N3 | 109 (69.4%) |
Performance status | |
 ECOG 0–1 | 138 (87.9%) |
 ECOG ≥ 2 | 19 (12.1%) |
EGFR mutation | |
 Exon 19 deletion | 74 (47.1%) |
 Exon 21 L858R substitution | 74 (47.1%) |
 Uncommon mutation | 6 (3.8%) |
 Complex mutation | 3 (2.0%) |
EGFR-TKI | |
 Gefitinib | 22 (14.0%) |
 Erlotinib | 67 (42.7%) |
 Afatinib | 68 (43.3%) |