Figure 2
From: Uracil-DNA glycosylase efficiency is modulated by substrate rigidity

(A) Inverse correlation between the measured specificity constants (kcat/KM) and α0, a fluorescence-derived experimental observable that measures the degree of base stacking in the region surrounding the uracil. (B) Correlation between kcat/KM and the NMR-measured exchange rate constants (kex) for the uracil imino proton. 