Table 1 Kinetic measurements for the interaction of vNAR T1 and rhTGF-β1.

From: First pan-specific vNAR against human TGF-β as a potential therapeutic application: in silico modeling assessment

Rmax

Chi (× 103)

Ka (× 10+4 M-1 s-1)

Kd (× 10–4 M-1 s-1)

KD (10–8 M)

730.6

1.33

3.227

33.17

10.28

737.1

1.28

3.357

33.55

9.99

760.6

1.27

3.228

27.65

8.56

Mean

1.29

3.27

31.34

9.61

  1. The association (Ka) and dissociation (Kd) rate constants and the equilibrium dissociation constant (KD) are shown. The results correspond to three independent assays.
Back to article page