Table 1 Comparison of demographic characteristics of influenza A positive patients sampled by the general UVRI-NIC surveillance programme whose viral swabs were successfully or not sequenced.

From: Phylogenomic analysis uncovers a 9-year variation of Uganda influenza type-A strains from the WHO-recommended vaccines and other Africa strains

Variable

Subgroup

Total [N]

Successfully Sequenced [n%]

Un-sequenced [n%]

P-value

Subtype

H1N1pdm09

588

106 [18.03]

482 [81.97]

< 0.0001*

H3N2

1190

105 [8.82]

1085 [91.18]

H1N1

29

0 [0]

29 [100]

Case

ILI

1196

139 [11.62]

1057 [88.38]

0.9809

SARI

611

72 [11.78]

539 [88.22]

Gender

Male

951

120 [12.62]

831 [87.38]

0.2149

Female

856

91 [10.63]

765 [89.37]

Age [years]

1 month to < 2

589

66 [11.21]

523 [88.79]

0.5851

2 to < 5

635

84 [13.23]

551 [86.77]

5 to < 15

338

39 [11.54]

299 [88.46]

15 to < 50

222

20 [9.01]

202 [90.99]

50 to < 65

15

2 [13.33]

13 [86.67]

≥ 65

7

0 [0]

7 [100]

No age data

1

  

Sample origin, by year

 2010

Central

81

20 [24.69]

61 [75.31]

0.5986

Northwest

5

2 [40]

3 [60]

 2011

Central

106

29 [27.36]

77 [72.64]

0.5451

Eastern

1

0 [0]

1 [100]

Northwest

9

4 [44.44]

5 [55.56]

Western

8

1 [12.5]

7 [87.5]

 2012

Central

193

14 [7.25]

179 [92.75]

0.5272

Eastern

18

0 [0]

18 [100]

Northwest

21

2 [9.52]

19 [90.48]

Western

10

1 [10]

9 [90]

 2013

Central

67

14 [20.9]

53 [79.1]

0.9346

Eastern

3

1 [33.33]

2 [66.67]

Northwest

10

2 [20]

8 [80]

Western

4

1 [25]

3 [75]

 2014

Central

218

18 [8.26]

200 [91.74]

0.004*

Eastern

46

0 [0]

46 [100]

Northwest

35

1 [2.86]

34 [97.14]

Western

61

11 [18.03]

50 [81.97]

 2015

Central

192

18 [9.38]

174 [90.62]

0.6795

Eastern

42

6 [14.29]

36 [85.71]

Northwest

19

2 [10.53]

17 [89.47]

Western

39

5 [12.82]

34 [87.18]

 2016

Central

139

13 [9.25]

126 [90.65]

0.0085*

Eastern

6

3 [50]

3 [50]

Northwest

15

0 [0]

15 [100]

Western

21

0 [0]

21 [100]

 2017

Central

271

28 [10.33]

243 [89.67]

0.3299

Eastern

22

0 [0]

22 [100]

Northwest

11

0 [0]

11 [100]

Western

35

4 [11.43]

31 [88.57]

 2018

Central

33

11 [33.33]

22 [99.67]

0.0555

  1. Initially, there were 1800 positives for a single influenza A subtype (H1, H1N1pdm09 and H3N2) in the UVRI-NIC dataset. After excluding one duplicated H1N1pdm09 viral sample (ARU0583), there remained 1799 positive A samples. We included 8 successfully sequenced samples that tested and were reported as positive in the laboratory dataset (used for sample randomization) but were reported as negative in the UVRI-NIC dataset. Therefore, the demographic characteristics presented in this table were for 1807 patients recorded in the UVRI-NIC dataset. 234 of the 1807 patient’s viral swabs were sampled for whole genome sequencing, and 215 of the 234 were successfully sequenced. However, four sequenced viruses (ARU0587, EBB2521, KIB0497, and KSW0631) lacked complete demographic data so we present data for only the 211 viruses that were successfully sequenced with complete data.
  2. Percentage number of sequenced or un-sequenced swabs are in [italics]. P-values showing significant differences between compared groups (< 0.05) are indicated in bold with a star (*).