Table 2 Cox proportional hazard regression analysis of factors associated with mortality in CPA glioblastomas.
From: An integrative survival analysis and a systematic review of the cerebellopontine angle glioblastomas
Variables | Univariable analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | |
Age | ||||||
Adult | 1.0 | 1.0 | 1.0 | |||
Pediatric | 1.95 | 0.69–5.45 | 0.204 | |||
Gender | ||||||
Female | 1.0 | 1.0 | 1.0 | |||
Male | 0.74 | 0.25–2.24 | 0.599 | |||
Hydrocephalus on admission | ||||||
Present | 1.0 | 1.0 | 1.0 | |||
Absent | 2.94 | 1.06–8.33 | 0.038 | 3.57 | 1.07–11.1 | 0.038 |
Tumor origins | ||||||
Exophytic | 1.0 | 1.0 | 1.0 | |||
Nerve root entry zone | 0.92 | 0.29–2.97 | 0.89 | |||
Tumor size | ||||||
< 3 cm | 1.0 | 1.0 | 1.0 | |||
> 3 cm | 2.38 | 0.63–8.99 | 0.200 | |||
Surgery | ||||||
STR or biopsy | 1.0 | 1.0 | 1.0 | |||
GTR | 0.70 | 0.16–3.13 | 0.64 | |||
Adjuvant treatment | ||||||
Chemotherapy | 0.18 | 0.04–0.65 | 0.009 | 0.44 | 0.07–2.86 | 0.393 |
Radiation therapy | 0.08 | 0.02–0.29 | < 0.001 | 0.12 | 0.02–0.59 | < 0.01 |