Figure 4 | Scientific Reports

Figure 4

From: Fate of arsenicals in mice carrying the human AS3MT gene exposed to environmentally relevant levels of arsenite in drinking water

Figure 4

Concentrations of MAs in tissues of humanized (Hs) and wild-type (WT) male and female mice after 4-week exposure to 25-ppb (A, C) or 400-ppb (B, D) of inorganic arsenic in drinking water. Each bar and whisker represent mean and SEM value, respectively. For 25-ppb exposure, N = 6 for Hs males and WT males, and N = 8 for Hs females and WT females. For 400-ppb exposure, N = 7 and 8 for Hs males and WT males, respectively, and N = 10 and 11 for Hs females and WT females, respectively. Horizontal line marks significant difference between genotypes for individual tissue; asterisk marks significant difference between males and females of the same genotype (p < 0.05).

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