Figure 2
From: Sympathetic neurons secrete retrogradely transported TrkA on extracellular vesicles
Morphology and sizing of EVs by cryo-EM. (A) Cryo-EM micrographs from the P20 (top row) and P100 (bottom row) fractions. Different types of EVs are annotated for easier appreciation of diverse EV morphologies. (B) Size distribution histogram for all measured EVs from cryo-EM micrographs (P20: n = 193 EVs, mean diameter 146.62 nm; P100: n = 360 EVs, mean diameter 152.59 nm). The left histogram (black bars) is the sizing of the P20 fraction, and the right histogram (gray bars) is the sizing of the P100 fraction separated out from the histogram below. Data is from three biological replicates and the scale bar is 100 nm for all images.
