Table 3 Correlations between lung function and surrogate indexes of body iron content.

From: Pulmonary function in patients with transfusion-dependent thalassemia and its associations with iron overload

Measurements

FVC (% Pred)

FEV1 (% Pred)

FEV1/FVC (%)

TLC (% Pred)

DLCO/VA (% Pred)

Serum ferritin

rho = − 0.04

p = 0.69

rho = − 0.06

p = 0.56

rho = − 0.06

p = 0.53

rho = − 0.08

p = 0.47

rho = − 0.19

p = 0.06

MRI cardiac T2* relaxation time

rho = 0.32

p = 0.03

rho = 0.30

p = 0.04

rho = 0.03

p = 0.86

rho = 0.33

p = 0.03

rho = − 0.07

p = 0.67

MRI liver T2* relaxation time

rho = 0.08

p = 0.64

rho = 0.03

p = 0.88

rho = -0.09

p = 0.60

rho = 0.09

p = 0.62

rho = 0.02

p = 0.89

  1. Correlations were performed by Spearman’s rank correlation.
  2. FVC, forced vital capacity; FEV1, forced expiratory volume in 1 s; TLC, total lung capacity; DLCO, diffusing capacity of the lung for carbon monoxide; VA, alveolar volume; MRI, magnetic resonance imaging.
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