Table 4 Brief Multilevel linear random-effects models to identify factors associated with neurological, digestive, respiratory, heart, and other symptoms.
Factors | Neurological symptoms | Digestive symptoms | Respiratory and heart symptoms | Other symptoms | ||||
|---|---|---|---|---|---|---|---|---|
Coef | p-value | Coef | p-value | Coef | p-value | Coef | p-value | |
Socio-economic | ||||||||
 Gender (Female vs Male -ref) | −0.35 |  < 0.001 | 0.06 |  < 0.001 |  |  | −0.19 |  < 0.001 |
 Age (unit: age) |  |  | −0.002 | 0.005 |  |  |  |  |
 Provinces (Southeast region -ref) | ||||||||
 Red River Delta | −0.28 | 0.023 |  |  | −0.16 | 0.019 |  |  |
 North Central Region |  |  |  |  | −0.15 | 0.029 |  |  |
 South Central Coast |  |  | 0.06 | 0.005 | −0.11 | 0.023 |  |  |
 Mekong Delta Region |  |  | 0.07 | 0.001 |  |  |  |  |
 Smoking (Yes vs No -ref) |  |  |  |  |  |  | 0.06 | 0.002 |
 Alcohol (Yes vs No -ref) | 0.13 |  < 0.001 |  |  |  |  |  |  |
BMI Index (vs Underweight -ref) | ||||||||
 Normal |  |  |  |  | 0.06 | 0.007 |  |  |
 Overweight/Obese | −0.13 |  < 0.001 |  |  | 0.08 | 0.018 | 0.03 | 0.041 |
 Comorbidities (Yes vs No -ref) |  |  |  |  | 0.24 |  < 0.001 |  |  |
 COVID-19 infection characteristics | ||||||||
COVID-19 infection period (vs Less than 7Â days -ref) | ||||||||
 7–14 days | 0.12 |  < 0.001 | −0.01 | 0.048 | 0.06 | 0.002 | 0.03 | 0.011 |
 More than 14 days | 0.20 | 0.011 | 0.06 | 0.03 | 0.15 | 0.003 | 0.09 | 0.001 |
Time since COVID-19 onset (vs 1Â month -ref) | ||||||||
 1–4 months | 0.12 | 0.001 | −0.04 | 0.001 | −0.06 | 0.007 |  |  |
 4–6 months | 0.13 | 0.023 |  |  |  |  | −0.04 | 0.033 |
Severity of COVID-19 at the onset (vs asymptomatic -ref) | ||||||||
 Mild | 0.26 |  < 0.001 |  |  | 0.17 |  < 0.001 |  |  |
 Moderate | 0.56 |  < 0.001 | 0.07 | 0.004 | 0.40 |  < 0.001 | 0.10 |  < 0.001 |
 Severe |  |  |  |  | 0.39 | 0.001 |  |  |
Prevalence of case in region (vs Low -ref) | ||||||||
 Medium |  |  | 0.03 | 0.038 |  |  |  |  |
Post-COVID-19 symptoms | ||||||||
 Neurological symptoms | – | – | 0.07 |  < 0.001 | 0.25 |  < 0.001 | 0.12 |  < 0.001 |
 Digestive symptoms | 0.40 |  < 0.001 | – | – | 0.38 |  < 0.001 | 0.20 |  < 0.001 |
 Respiratory and heart symptoms | 0.43 |  < 0.001 | 0.12 |  < 0.001 | – | – | 0.07 |  < 0.001 |
 Other symptoms | 0.55 |  < 0.001 | 0.16 |  < 0.001 | 0.18 |  < 0.001 | – | – |