Table 1 Baseline characteristics of patients with AS obtained using the electronic medical record management system for ASDAS assessment.
AS patients, n = 652 | Eligible AS patients with ≥ 3 continuous assessment, n = 201 | |
|---|---|---|
Age at first ASDAS assessment, years, Mean ± SD (n/N) | 43.1 ± 13.7 (652/652) | 43.3 ± 13.4 (201/201) |
Gender | ||
Female | 27.1 (177/652) | 26.4 (53/201) |
Male | 72.9 (475/652) | 73.6 (148/201) |
Age at AS diagnosis, years, mean ± SD (n/N) | 26.8 ± 11.5 (652/652) | 27.0 ± 11.2 (200/201) |
Disease duration, years, mean ± SD (n/N) | 16.4 ± 11.7 (652/652) | 16.3 ± 11.6 (200/201) |
HLA-B27 positive* | 88.7 (430/485) | 86.1 (136/158) |
Biologics therapy | 31.1 (203/652) | 24.4 (49/201) |
Comorbidities* | ||
Hypertension, % (n/N) | 20.2 (131/648) | 21.5 (43/200) |
Diabetes mellitus, % (n/N) | 7.4 (48/650) | 4.5 (9/200) |
Hyperlipidemia, % (n/N) | 14.9 (96/644) | 16.2 (32/197) |
Hepatitis B, % (n/N) | 10.9 (71/649) | 9.5 (19/200) |
Hepatitis C, % (n/N) | 2.3 (15/650) | 3.0 (6/200) |
Renal insufficiency, % (n/N) | 3.2 (21/651) | 2.0 (4/200) |
Gout, % (n/N) | 4.5 (29/651) | 3.0 (6/200) |
Coronary artery disease, % (n/N) | 3.2 (21/650) | 3.5 (7/200) |
Stroke, % (n/N) | 0.3 (2/651) | 0.5 (1/200) |
Periodontitis, % (n/N) | 18.7 (121/646) | 19.6 (39/199) |
Osteoporosis, % (n/N) | 6.7 (42/630) | 6.2 (12/193) |
Tuberculosis history, % (n/N) | 6.9 (45/648) | 6.1 (12/198) |
AS-related manifestations | ||
Uveitis, % (n/N) | 25.8 (168/651) | 26.8 (53/198) |
Psoriasis, % (n/N) | 6.8 (44/649) | 11.1 (22/199) |
Crohn's disease, % (n/N) | 0.0 (0/650) | 0.5 (1/200) |
Ulcerative colitis, % (n/N) | 0.5 (3/651) | 1.0 (2/199) |
Peripheral arthritis, % (n/N) | 19.3 (125/646) | 21.5 (43/200) |
Enthesitis, % (n/N) | 14.4 (92/641) | 18.3 (36/197) |
Dactylitis, % (n/N) | 2.3 (15/652) | 2.0 (4/199) |
Family history | ||
AS-First degree relatives, % (n/N) | 18.7 (119/636) | 15.5 (30/193) |
AS-Secondary degree relatives, % (n/N) | 29.0 (185/639) | 24.5 (48/196) |
Psoriasis, % (n/N) | 4.2 (27/643) | 5.1 (10/196) |
Psoriatic arthritis, % (n/N) | 0.6 (4/641) | 1.0 (2/194) |
Uveitis, % (n/N) | 4.7 (30/643) | 6.1 (12/196) |
Crohn’s disease, % (n/N) | 0.0 (0/641) | 0.0 (0/195) |
Ulcerative colitis, % (n/N) | 0.3 (2/641) | 0.5 (1/195) |
Rheumatoid arthritis, % (n/N) | 6.0 (38/638) | 5.7 (11/194) |
Systemic Lupus Erythematosus, % (n/N) | 3.0 (19/641) | 2.6 (5/195) |
Sicca syndrome, % (n/N) | 2.5 (16/641) | 3.1 (6/195) |
Past history | ||
Total hip replacement, % (n/N) | 3.8 (25/652) | 2.0 (4/200) |
Total knee replacement, % (n/N) | 0.6 (4/652) | 0.5 (1/200) |
Fracture, % (n/N) | 10.7 (70/652) | 7.5 (15/200) |
Palindromic rheumatism, % (n/N) | 1.1 (7/652) | 0.5 (1/200) |
