Figure 10 | Scientific Reports

Figure 10

From: An agent-based approach for modelling and simulation of glycoprotein VI receptor diffusion, localisation and dimerisation in platelet lipid rafts

Figure 10

Enforced GPVI dimerisation reduces the confined domain area for a given GPVI localisation ratio. Plot of simulation of GPVI localisation in the presence of a confined domain with variable occupied area. Note the near linear increase of receptors inside the confined domain when this area increases. The reported value of GPVI with restricted movements40 is about 50%, pointing to a confined domain size of 20–21%. In the presence of dimerisation, this area slightly decreases to 19–20%, with a kb = 0.000625 and kd = 0.000125 (least square regression analysis).

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